Yes - this has happened to me recently (I had a bad reaction first to citalopram and then venlaflacine).
In both cases, the drug caused anxiety levels to soar through the roof to a point where it was (a) almost unbearable to be awake, and (b) almost impossible to sleep.
In each case I gave it about 3 weeks (which is reckoned to be the usual acclimatization period for these drugs before contacting my doctor, explaining the symptoms and asking to try something else (a week's "cold turkey" being required each time to clear the previous drug from my system before starting the next).
I am now taking a non SRI typed medication which does actually seem to be helping although again the side effects (aching muscles & joints, cramps & nerve spasms, horrific nightmares, tiredness) were all pretty severe for the first 3 weeks and are still present (although in reduced form) 5 weeks in.
My advice is to speak with your doctor sooner rather than later. He/she well know what the usual acclimatization period is for your medication, and will also know about the most commonly experienced side effects / problems during and after that period. It may be simply that the dosage needs to be changed, or (as in my case) that the medication is fundamentally incompatible with your body chemistry in some way and that it's time to try something else.
It may be that your bus is just around the corner (in which case stoicism has a high chance of success), or it maybe that the place you've been patiently waiting is not actually a bus stop at all (in which case stoicism as a strategy is doomed to failure !).
Talk to your doctor with the aim of getting some idea of which situation applies here.
Courage and good fortune :-)
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